Interpretation of the Varga Plant from the Doctor Who teaser - Mission to the Unknown - a single episode that set up events for the epic 12 part Dalek's Masterplan. (1965)
If anyone was snagged by a Varga Thorn they would rapidly lose their reason and become murderous. Death wasn't even an escape from the horror as the corpse of the victim would slowly turn into a new Varga Plant.
Classic Body Horror.